GPCR assays

Endothelin Receptor Assays

Species: Human

Subtypes: ET1 (others available on request)

Assay Formats: Cell-based assay (ET1)

Services: HTS, single concentration / dose response studies, selectivity profiling

 

Endothelin 1 - Cell-based assay

Endothelin A cell based assay

Figure 1: Dose response curve for agonist Endothelin 1 in an Endothelin-1 cell-based assay. Approximate EC50 19.7 nM.

 

Endothelin 1 - Cell-based assay

Endothelin A cell based assay

Figure 2: Dose response curve for antagonist Cl1020 in an Endothelin-1 cell-based assay. Approximate IC50 0.82 nM.


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