Calcium channel assays

Calcium Channel Screening Services

Calcium Channels

Voltage-gated calcium channels (VGCC) are found in excitable cells such as muscle and neurons and consist of an α1 ion-conducting pore which forms a complex with associated subunits (α2δ, β1-4, γ). There are various voltage-gated calcium channel α1 subtypes, namely the L-type (Cav1.1, 1.2, 1.3, 1.4), P/Q-type (Cav2.1), N-type (Cav2.2), R-type (Cav2.3) and T-type (Cav3.1, 3.2. 3.3) channels.

SB Drug Discovery has developed stable calcium channel cell lines and validated screening & profiling assays for HTS, lead optimization studies and selectivity profiling. Our assays have been validated by experienced in-house electrophysiologists using rigorously optimized SOPs to ensure data of the highest quality and consistency.

To discuss your next ion channel project or to receive a quote, visit our contact page or call +44 141 587 6100.


Calcium channel assays

Channel Species Fluorescence Assay Manual Patch Clamp QPatch SyncroPatch
Cav1.2 Human Green Dot Green Dot Green Dot Orange Dot
Cav2.1 Human Green Dot Green Dot Green Dot Orange Dot
Cav2.2 Human Orange Dot Green Dot Green Dot Orange Dot
Cav3.1 Human Green Dot Green Dot Green Dot Orange Dot
Cav3.2 Human Green Dot Green Dot Green Dot Orange Dot